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and wound healing in Sprague Dawley rats

In DFU, notch pathway dysfunction can lead to inhibition of cell differentiation, proliferation disorders, and reduced angiogenesis, all of which interfere with diabetic wound healing

doi: 10.1073/pnas.100114897

Largely through the work of Dr

CD34 defines melanocyte stem cell subpopulations with distinct regenerative properties

Indeed, CiiiDER analysis (Gearing et al., 2019) revealed that there are predicted promoter-binding sequences that distinguish the 61 shared target genes from the top 200 ATF4-dependent genes induced by the ISR alone (Figure 2A supplementary table 2)