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Safety profiles remain based on short-term animal studies rather than lifelong human observation

Clinical applications and utility of cell-free DNA-based liquid biopsy analyses in cervical cancer and its precursor lesions

Boretto M, Cox B, Noben M, Hendriks N, Fassbender A, Roose H, Amant F, Timmerman D, Tomassetti C, Vanhie A, Meuleman C, Ferrante M, Vankelecom H (2017) Development of organoids from mouse and human endometrium showing endometrial epithelium physiology and long-term expandability

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Patients did not require dopaminergic therapy at the initiation of the trial

Treatment of mice with THC for seven consecutive days caused phosphorylation of p38 MAPK [45]