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Upon activation, the p38 MAPK signaling pathway induces robust oxidative stress response and triggers the release of a plethora of inflammatory factors, including TNF-, IL-1, and IL-6

(PubMed) Sandstead HH, Frederickson CJ, Penland JG

Carter BZ, Schober WD, McQueen T, Andreeff M

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Mice treated with Au/Cu-TCPP (Fe)@RSL3-PEG-iRGD had the longest survival with a median survival time of 60 days, and only a small number of tumor cells retaining proliferative activity

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