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These findings suggest that obesity and metabolic syndrome accelerate CKD progression, which is associated with abnormal energy metabolism and may be due to mitochondrial dysfunction

10.1126/science.aat6280 Science 57 Heintz-BuschartA.WilmesP

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Protein (50 M) was incubated with 125 M ML162 (pure ( S )-enantiomer) for 30 min at RT, then centrifuged (3 min, 3220 x g)

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