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These considerations support the development of rational, multi-target strategies aimed at simultaneously limiting cardiomyocyte death and secondary inflammation, while future translational studies are needed to define safety, optimal dosing, and clinical relevance of cell deathtargeted therapies in myocardial ischemia/reperfusion injury

Mol Med (Cambridge, Mass) 1:806820 Wolf G, Aumann N, Michalska M, Bast A, Sonnemann J, Beck JF, Lendeckel U, Newsholme P, Walther R (2010) Peroxiredoxin III protects pancreatic cells from apoptosis

MGST1 overexpression ameliorates mitochondrial dysfunction and ferroptosis during myocardial ischemia/reperfusion injury after heart transplantation

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Despite these two proteins sharing universal roles in PTS carbon acquisition, they have diverse functions, and per our results, phenotypes

Before deciding between a compounded peptide and a research-grade laboratory peptide, see what a licensed clinic protocol looks like in practice