glutathione peroxidase polymorphism The role of peroxidase-1 in health and disease Trait: Oxidative Stress Risk (GPx-1)

doi:10.1002/oby.20609 Kiilerich K, Gudmundsson M, Birk JB, Lundby C, Taudorf S, Plomgaard P, Saltin B, Pedersen PA, Wojtaszewski JF, Pilegaard H (2010) Low muscle glycogen and elevated plasma free fatty acid modify but do not prevent exercise-induced PDH activation in human skeletal muscle

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mTOR: from growth signal integration to cancer, diabetes and ageing

A unique characteristic of presence of catalytic cysteine in the active site help them in thioltransferase activity instead of GSH transfer activity

Notably, supplementation with ferrostatin-1 or trolox, both of which are radical-trapping antioxidants and potent inhibitors of ferroptosis, rescued survival but not proliferation under cystine-free conditions (Extended Data Fig

Naive control rats (unexposed and untreated) underwent identical measurements concurrently with the experimental groups and served as companion controls