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Neurofibrillary tangles are the characteristic hallmark of Alzheimer`s disease and related neurodegenerative Tauopathies in which Tau is the main component [5, 6]

Fragment-Based Drug Discovery: Lessons and Outlook

Metabolic rate increases occur through multiple mechanisms including brown adipose tissue activation

in contrast, knocking out LPCAT3 does not confer robust protection against ferroptosis, suggesting that these family members may have compensatory mechanisms [41]

Similarly, in the 6GGE-crocin complex, crocin exhibited stable and flexible binding throughout the trajectory

GST P1-1 also has a role in protection and cell survival after exposure to H2O2 but not against UV-induced apoptosis [1]