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These neuropeptides interact with MCs to initiate neurogenic inflammation and stimulate the release of type 2 cytokines such as IL-4 and IL-13, thereby exacerbating cutaneous inflammation and pruritus (131)

doi:10.1067/mjd.2003.155 PubMed | Crossref | Google Scholar Errichetti E, Maione V, Stinco G

By contrast, my brother Giless staunch incapacity to pardon us for the unwelcome attentions that our wayward son has visited upon his own family is a grudge I treasure, if only for its frankness