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Description

Purification and characterization of factors produced by Aspergillus fumigatus which affect human ciliated respiratory epithelium

2020;158(3):562-572.e12.

Dhege CT, Kumar P, Choonara YE

It was administered to male SpragueDawley rats before MCAO surgery, and after 24 h, it mitigated neurological impairments and reduced thioredoxin expression [150]

Administration of 3-hydroxyanthranilic acid (3-HAA), a downstream tryptophan metabolite, ameliorated the symptoms of EAE by increasing the number of Treg cells and inhibiting the functions of Th1/Th17 cells (82)

OP is currently in Phase II trials and a small open-label study has shown that the administration of OP was safe and resulted in a marked reduction in ammonia concentration [73]