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To compromise IRI and alloimmune responses and allow removal of accumulating toxic metabolites during ex vivo perfusion, the integration of leukocyte filters has been tested for several organs

Nicotinic acid: an old drug with a promising future

Single cell analysis of ATO uptake and cytotoxicity has been achieved using time-resolved ICP-MS with cisplatin as a viability dye and lanthanide-tagged antibodies targeting differentiation (anti-CD11b, conjugated to 146 Nd) and apoptosis (Annexin-V, conjugated to 163 Dy) markers (Fig

The percentage of late apoptosis in THJ-16 cells increased from 5.49% for untreated cells to 63.43% for treated cells, while the corresponding percentage in CAL-62 cells increased from 16.72 to 69.88%

The novel anti-ferroptosis role of GPx4 in eliminating lipid peroxidation in AS Once selenoproteins are overexpressed, vascular endothelium damage can be prevented in AS-associated cardiovascular diseases [60]

Elevated NADH inhibits mitochondrial -oxidation and suppresses fatty acid synthesis, resulting in intracellular lipid accumulation (You and Arteel, 2019