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Alhaider IA, Aleisa AM, Tran TT, Alkadhi KA

By directly binding RAF-1 and MEK, RKIP interferes with the formation of the kinase-substrate complex, thereby inhibiting the phosphorylation of MEK, ultimately plays a role in inhibiting RAF/MEK/ERK signaling pathway

Sturkie's avian Physiology

Bacteria can develop antibiotic resistance via genetic mutations or through the vertical or horizontal transfer of resistance genes to other strains within and outside the species [15]