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In 2019, a team from the Allen Institute for Artificial Intelligence (AI2) developed the SUPP.AI database to identify and catalog supplement-drug interactions, including those involving herbal medicines, using machine learning and natural language processing (NLP) techniques [164]

NADPH oxidases generate ROS as O 2 or H 2 O 2 depending on the isoform and contextNOX1/2/3 primarily release O 2 that dismutates to H 2 O 2 , NOX4 predominantly yields H 2 O 2 and Ca-activated NOX5 together with epithelial DUOX1/2 contribute directly to H 2 O 2 production at barrier surfaces (Kim and Moon 2024)

Respiratory enzymes in oxidative phosphorylation

Hao D, Qu M, Nourbakhsh M (2021) Experimental study of burn damage progression in a human composite tissue model

Fer-1 has also been shown to alleviate DSS-induced colitis through the NRF2/HO-1 pathway (72)

There are two main limitations of the redox array: firstly, a positive signal on the array could also be due to a biotinylated protein that binds to the antibody specific ligand thus resulting in a false positive signal