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4.8
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Description

Leamon (Endocyte Inc., USA) followed with a presentation entitled Translational struggles of folate SMDCs: New learning and future directions in which he provided a summary spanning nearly 20 years of cancer-targeted small molecule drug conjugate research, with special emphasis on EC1456, a folate-tubulysin conjugate that was tested in a phase 1 trial [51]

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While the mechanistic basis of age-associated elevation of aneuploidy rates is undoubtedly complex, several contributing factors have been identified

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