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Cox proportional hazards regression (N = 386, C-index = 0.793) identified baseline albumin as the only statistically significant independent predictor of mortality (HR 0.232, 95% CI: 0.110.49, p 18, absence of HCC, and baseline albumin 2.5 g/dL

The UPR, which shares molecular machinery with the integrated stress response, halts cap-dependent translation, induces expression of ER chaperone proteins and can lead to death if the stress is not resolved

Rationally-based therapeutic disease modification in systemic sclerosis: Novel strategies

[DOI] [PMC free article] [PubMed] [Google Scholar] 110.Abd, G

The inflammatory manifestations in bone and skin are considered to be autoimmune in etiology

doi: 10.1126/science.1223899