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10.1038/sj.bjc.6600176 Br

MARCH was a 26-week, randomized, placebo-controlled (PBO), Phase 3 trial of maralixibat (MRX), an ileal bile acid transporter (IBAT) inhibitor, that achieved its primary and key secondary endpoints of pruritus and sBA reduction for individuals across the broadest range of PFIC types studied

In a press release announcing RiVives approval, FDA Commissioner Robert Califf stated the regulators commitment to making naloxone accessible and encouraged other manufacturers of these products to discuss potential nonprescription development programs with the FDA

Observational data suggest sharp increases in mortality, AKI, and myocardial injury below DAP thresholds around 4550 mmHg

Polyethylene glycol loxenatide injection (GLP-1) protects vascular endothelial cell function in middle-aged and elderly patients with type 2 diabetes by regulating gut microbiota

Studies have shown that applying it topically can increase collagen production and might even increase firmness