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By employing the hypergeometric distribution, the probability of a frequency greater than k under completely random conditions was calculated using the following formula: p=1i=0k1p(i|n,m,N) where, p(i|n,m,N)=n!(Nn)!m!(Nm)!(ni)!i!(nm)!(Nnm+i)!N

Dreyer BA, Amer T, Fraser M

Brief inhalation of nitric oxide increases resuscitation success and improves 7-day-survival after cardiac arrest in rats: a randomized controlled animal study

No one really wants to keep them around (fire hazards that they are)

Importantly, therapeutic manipulation of any single node in this circuit yields highly variable outcomes that depend on tumor type, microenvironmental pressures, therapy modality (ICB versus ACT), and timing of intervention

Secondary disorders are only a manifestation of an underlying CNS disease