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During the late 1940s and 1950s, a series of largely uncontrolled studies in patients with slow-healing wounds, such as vascular ulcers and pressure (decubitus) ulcers, reported that the application of topical SCC promoted healing more effectively than other commonly used treatments (40, 41)

Taken together, these technical challenges explain why genetic transformation in amaranth is primarily used for functional validation studies and specialized metabolite production, rather than for generating commercial cultivars (Joshi et al., 2020

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Glycosaminoglycan-peptide complex (GP-C) To enhance therapeutic delivery in OA treatments, Sodhi and Panitch 120 developed a glycosaminoglycan (GAG)-based NPs system for the encapsulation of cationic peptides, specifically focusing on the KAFAK sequence