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10.1038/s41598-024-67557-x 112 LiH.JingY.QuX.YangJ.PanP.LiuX.et al (2023a)

In overdose, however, the capacity of these conjugation pathways is overwhelmed and acetaminophen is oxidized by a liver P-450 cytochrome CYP3A4 to N -acetyl benzoquinoneimine (NABQI)