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Furthermore, the hydrophilic FUDR and the hydrophobic CPT form a amphiphilic prodrug, which promotes self-assembly and thereby increases the drug loading capacity of the two drugs

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Cui et al., Detoxification Cisplatin is inactivated by conjugation with glutathione through the GSTs

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Ecotoxicol Environ Saf 45:198207 Cairns NG, Pasternak M, Wachter A, Cobbett CS, Meyer AJ (2006) Maturation of Arabidopsis seeds is dependent on glutathione biosynthesis within the embryo

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JNK signaling confers tolerance to oxidative stress and extends lifespan in Drosophila

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doi: 10.1111/jfbc.14451 26

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