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Notably, DA, as a neurotransmitter containing catecholamines, is not only easily oxidized but also generates free radicals and toxic metabolites, including ROS, dopaquinone (DAQ), and 3,4-dihydroxyphenylacetaldehyde (DOPAL) (Vaarmann et al., 2010

The optical density of each well was measured using a microplate reader at 550 nm

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Blood-Brain Barrier Permeability Structural Advantage: Unlike many peptides that struggle to penetrate the blood-brain barrier, it's small molecular size and lipid solubility allow it to cross easily

FIGURE 2 3.1 Parkinsons disease Parkinsons disease (PD) is mainly defined by the gradual degeneration of dopamine-producing neurons located in the iron-rich substantia nigra