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Therefore, this review aims to summarize the regulation of metabolism on inflammatory response and oxidative stress in the pathogenesis of ARDS, explain the regulatory effects of various metabolites and the mechanisms involved, and finally introduce the current potential therapeutic drugs for metabolic regulation in ARDS

Ethics statement The animal study was approved by The Committee on the Use of Live Animals in Teaching and Research (CULATR) of the University of Hong Kong (CULATR Ref

incomplete 12-month follow-up: n = 8

We also analyzed ChIP-seq datasets of histone H3 modifications, including H3K4me3, H3K4me1, H3K27ac, and H3K27me3, previously generated by us from human HEK293T cells 27

It is derived from a partial sequence of Body Protection Compound, a protein originally identified in gastric juice, and is widely studied in laboratory settings for its stability and activity in biological repair models

The extracellular matrix (ECM) of the heart is composed primarily of twisted perimysial collagen fibers (but may also include elastin and collagen fibrils) and adhesive glycoproteins (such as fibronectin, laminin, and proteoglycans), which are arranged parallel to the long axis of the cardiac muscle