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-synuclein is translocated to mitochondria and directly interacts with mitochondrial proteins including ATP synthase to lower mitochondrial inner membrane potential, thus altering neuronal energy metabolism and opening mitochondrial death channels [24,26]

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This is why prompt veterinary attention when a sick cat is not eating, coughing a lot, or feverish is importantso that treatment can be started as soon as possible and improve the chances of recovery

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Thrombospondin-I is a critical modulator in non-alcoholic steatohepatitis (NASH)