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(Volkmann 2017

By influencing inflammatory pathways and cellular stress responses, metformin may aid in preserving cartilage and soft tissues within the joints, which are often vulnerable to damage caused by inflammation (113, 114)

However, if side effects are limiting, staying at the current dose or reducing the dose is appropriate

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L-methionine serves as a precursor to glutathione, one of the body's most important antioxidants, further supporting liver detoxification and cellular protection