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Apart from that, ceramides, which have been shown to correlate with lipid-induced hepatic insulin resistance, were also reported to be a target of SFN (Teng et al., 2019)

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doi: 10.1136/thx.53.7.594 135 MatsumotoS.SingleyC

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Dietary and pharmacological modification of the insulin/IGF-1 system: exploiting the full repertoire against cancer

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Nature 429:417423

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These findings identify a previously unrecognized regulatory mechanism linking MAT2A to transcriptional control and metabolic reprogramming, and highlight MAT2A as a promising therapeutic target for osteosarcoma

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MSCs are pluripotent cells widely distributed across various tissues in the human body

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