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190,191 The C-terminus of MDM2 is crucial for export of wild-type p53 from the nucleus to the cytoplasm, where it is degraded via E3 ubiquitin ligases

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Sources of carnitine Although the body can produce enough carnitine to meet normal needs, certain conditions, such as restricted diets, metabolic disorders, or high levels of physical activity, can increase the demand for carnitine

Finally, apoptotic cells in advanced lesions appear to become poor substrates for efferocytosis

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