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Mechanistically, systemic hypertension induces arterial stiffness, which disproportionately increases afterload on the heart, leading to accelerated concentric LV hypertrophy and fibrosis (Samson et al., 2016)

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Streubel-Gallasch L, Giusti V, Sandre M et al (2021) Parkinsons disease-associated LRRK2 interferes with astrocyte-mediated alpha-synuclein clearance

Conventional antioxidants frequently encounter challenges, including limited permeability, poor aqueous solubility, instability, and low bioavailability (184)

4 Department of Public Health, Faculty of Health Sciences, The University of Bamenda, Cameroon