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In addition to experimental evidence, the translational relevance of MNP cardiotoxicity calls for proactive public health measures and regulatory oversight

The images were processed using ImageJ or the LSM Image Examiner programme

Abbreviations APAP: Acetaminophen DILI: Drug-induced liver injury AILI: APAP-induced liver injury ND: Normal diet LPD: Low protein diet LMICs: Low-and middle-income countries DILI: Drug-induced liver injury GSH: Glutathione NAPQI: N-acetyl-p-benzoquinoneimine CYP2E1: Cytochrome P450 2E1 ALT: Alanine aminotransferase AST: Aspartate aminotransferase ALP: Alkaline phosphatase SOD: Superoxide dismutase TNF-: Tumor necrosis factor alpha IL-6: Interleukin 6 PK: Pharmacokinetics PCNA: Proliferating cell nuclear antigen References Acharya SK, Panda SK, Saxena A, Gupta SD

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