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We next synthesized small molecules that were metabolically stabile using methods to protect against peptidase action while maintaining biological activity

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Here, we studied a group of healthy elderly under scopolamine to test whether it elicits similar changes in brain connectivity as those observed in AD, thereby verifying a possible model of AD impairment

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A 15 l aliquot of proteinCIPp-18 mixture containing 8% sucrose was loaded into separate wells on the agarose gel and electrophoresis was carried out at 200 V/cm for ~ 35 min in running buffer (25 mM TrisHCl, pH 7.4)