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Acknowledgments This work was supported by a Discovery Project Grant from the Australian Research Council (ARC

8A and S12, N = 3), and with liposome-encapsulated drugs, a significant increase was seen in only 1 out of 3 trials, though non-significant trends towards increased lifespan were also seen under both conditions (Supplemental Table 6)

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Collectively, advancing the mechanistic understanding and therapeutic exploitation of the TAM-ferroptosis axis holds considerable promise for the next generation of precision immunometabolic cancer treatments

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Accepting that some degree of shadowing may be natural, particularly due to genetics or ageing, is also important for realistic expectations