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The treatment of 100 M peroxynitrite exposure for 48 h resulted in an obvious but moderate SGN loss, as there were 59.3 3.71% SGNs left compared with the control group (Figure 2B), and it was selected as the peroxynitrite treatment condition for all subsequent experiments

The MRM conditions (parent ion fragment ion

The role of catalase in mitigating oxidative stress underscores its utility as a therapeutic avenue in a spectrum of pathological states characterized by increased reactive oxygen species (ROS) production (Figure 1 and Figure 2)

Sautin YY, Johnson RJ (2008) Uric acid: the oxidant-antioxidant paradox

In neonatal lungs, mitochondria generate more ROS compared to adults (Kindermann et al., 2019), and neonatal animals also show greater tolerance to hyperoxic conditions than mature specimens (Perez et al., 2019)