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BPC-157s extensive publication record (100+ studies) provides the broadest preclinical safety dataset for either compound

10.3390/ijms251910319 41 KhassafiN.Azami TamehA.MirzaeiH.RafatA.BaratiS.KhassafiN.et al (2024)

FIGURE 7 7 Discussion 7.1 Limits of preclinical models and translational relevance While a growing body of preclinical evidence supports the therapeutic potential of redox-targeted antioxidants and stem cellderived EVs in mitigating oxidative stress and restoring ovarian function, significant translational hurdles remain before these strategies can be applied clinically in women

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This impact may be reinforced by mixing CH with restorative materials to create chitosan-based nanostructures

However, disease-associated SUOX mutations have revealed that heme binding may not be strictly required for SUOX activity 100