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This disease spectrum covers stages from early simple hepatic steatosis to metabolic-associated steatohepatitis (MASH), which can further progress to hepatocirrhosis and hepatocellular carcinoma (HCC) (Tincopa and Loomba, 2024)

Rather than finding a single best antioxidant target to support the regulation of age-related decline in redox state, we explore an activator of the cells balanced antioxidant/oxidative redox response, the transcription factor Nrf2 (nuclear erythroid factor-like 2)

As emerging pollutants, nano/microplastics (NPs/MPs), specifically 5 m polystyrene microplastics (PS-MPs), do not accumulate in the brain but significantly impair cognitive function in animal experiments