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Collectively, these findings highlight mitochondria as both biomarkers and actionable therapeutic targets to alleviate viral infectionassociated pathology and improve clinical prognosis

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M.HannonE.McQueenG

An increase in the nuclear translocation of CaMKIV/CREM decreases GPX4, which is accompanied by an increase in intracellular lipid-ROS, eventually leading to neutrophil iron apoptosis (170) ( Figure 3 )

Briefly, MODE-K IECs were silenced for 48 h with siGpx4 or siCtrl and washed with high-glucose DMEM (1% FCS, 1% penicillin/streptomycin, 25 mM HEPES)

Remyelination quality may also depend on the source of remyelinating cells