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TRAP1 is well studied in cancer since TRAP1 expression is tightly regulated in tumor cells (319), TRAP1 acts as a metabolic switch (320) by targeting and inhibiting succinate dehydrogenase (321), which is important for metabolic re-purposing and inflammatory responses (322)

A 125% increase in the GLP-1 and 59% decrease in blood glucose were observed

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2018;16:133 BioMed Central

280, 3438934392 10.1074/jbc.C500230200 [DOI] [PubMed] [Google Scholar] 18.Freidenberg, G.R., Henry, R.R., Klein, H.H., Reichart, D.R

Sermorelin is generally well-tolerated and does not inherently increase estrogen levels in a clinically significant way