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During PCOS progression, persistent inflammation also induces mitochondrial dysfunction, uncouples the electron transport chain, and promotes substantial ROS leakage (75)

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Addition of a single dose of 5 M Reversan 24 h prior to Venetoclax administration drastically sensitized MV4-11 and HL-60 cells to BCL-2 inhibition, resulting in a 3.9 and 6.5-fold decrease of the GI 50 , respectively (Fig

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