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Description

In September 2019, the US FDA approved an 8-week G/P regimen for cirrhotic patients, based on data from EXPEDITION-8 [107]

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Here, context, and the words themselves, show that the two different phrases have the same meaning

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To match the peak steady-state concentration, the loading dose can be calculated from equation (13): TARGET CONCENTRATION INTERVENTION: APPLICATION OF PHARMACOKINETICS & PHARMACODYNAMICS TO DOSE INDIVIDUALIZATION The basic principles outlined above can be applied to the interpretation of clinical drug concentration measurements on the basis of three major pharmacokinetic variables: absorption, clearance, and volume of distribution (and the derived variable, half-life)

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