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SKU: 31937136767
Price: 27.04 USD
Availability: InStock
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When combined with the BRAFV600E-inhibitor PLX4032 a robust repression in melanoid viability was obtained, establishing preclinical value of patient-derived melanoids for prognostic use of drug sensitivity and further underscoring the beneficial effect of Pin1-FOXM1 inhibitory peptides as anti-melanoma drugs

It has been established that the HMOX2 HW/GW mutant acts as an apo-HMOX2 mimic that allows us to study haem transfer dynamics, due to haem-binding at the HRM and the lack of haem in the catalytic core 49