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Increased plasma Beta-Hydroxybutyrate, preserved cerebral energy metabolism, and amelioration of brain damage during neonatal hypoxia ischemia with dexamethasone pretreatment

No dose-ranging trial was ever completed

In recent years, an increasing number of studies have focused on adjunctive therapeutic strategies aimed at further protecting dopaminergic neurons based on existing treatments, delaying disease progression, and improving patients quality of life

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Using nature or non-nature amino acid-bearing side-chain functional groups that can be directly coupled and forming covalent bonds to constrain the conformation of peptides is termed as one-component stapling strategy [45, 111]

Briefly, CO slices were treated with lipopolysaccharide (LPS) (Invivogen, San Diego, CA, USA, TLRL-3PELPS LPS) at 100 ng/mL for 3 h as a priming step