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Fluvastatin and lovastatin target the cholesterol pathway that plays a role in the prenylation of members of the PI3K/AKT/mTOR pathway and RAS, which could impact on the ability of RAS to activate BRAF [67], eventually causing a proliferation arrest

68,69 Once the cationic molecules contact with the endothelial cell surface, they adhere to it by adsorption

Kurose, Ms

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doi: 10.1111/j.1526-4610.2006.00311.x 221

However, exceeding the dosage may cause nausea, abdominal cramps, a fishy body odour, and diarrhoea in some individuals