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You perform a full skin exam and decide to biopsy one lesion

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However, the researchers noted that statistically significant effects were weak and in part could be due to incidental change in the placebo group

An additional uncertainty is the specicity of the modication, that is, whether the modi- ed cysteine residue is glutathionylated in vivo, rather than nitrosylated or a target of TRX (or some combina- tion of these modications)

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