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Chromatin immunoprecipitation sequencing and RNA sequencing identified a variety of autophagy genes (Atgs), including Atg2, Atg4, Atg7, and Atg10, as direct p53 target genes

The pathogenesis of subclinical thyroid dysfunction is often linked to autoimmune thyroiditis, particularly Hashimotos disease in the case of subclinical hypothyroidism [23]

ICANS, closely associated with CRS, results from the rupture of the BBB caused by cytokine-mediated endothelial activation, which leads to immune cell infiltration, stress in astrocytes and pericytes, excitotoxicity, and neuroinflammation

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ADR = Unknown, harmful, unpredictable, may be severe