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Figure 1 Biological Function of Lipoic Acid Quenching reactive oxygen species Based on the definition of an antioxidant provided by Halliwell and Gutteridge as being any substance that when present at low concentrations compared to those of an oxidizable substrate significantly delays or prevents oxidation of that substrate, LA has several unique characteristics among other natural antioxidants to fulfill this criterion (Petersen Shay et al., 2008)

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ATRA, which works via RXR, induced the expression of GS selectively and GSH levels in myeloid-derived suppressor cells [141]

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doi: 10.1111/cpr.13245 48 BlackDMRosenCJ

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