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Disulfide conjugation protocol The pure thiol-containing peptide and thiopyridyl-activated linker-functionalized MK-801 were dissolved in DMF (2 ml) and buffer consisting of 6 M guanidine and 1.5 M imidazole in H 2 O at pH 8 (200 l) and agitated for at least 2 h

More help The WOE analysis indicates that many KEs and KERs lack some experimental evidence, especially that showing that without one KE, the following KE will be affected or non-existent

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Its levels can serve as a biomarker of neurotransmitter activity [42], especially in neurobiological research involving emotion, motor control, and reward mechanisms

Eur Neuropsychopharmacol 29:471481

But what exactly does it mean