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10.1056/NEJMoa1606038 127

Despite the promising efficacy observed in Th- MYCN -derived 3D spheres, administration of the compounds resulted in gastrointestinal toxicity, including blocked intestine and stomach enlargement, necessitating early termination of the experiment

insoluble in non-polar solvents Storage & Stability Shelf life: 1.5 years from manufacture (21 C) Store at ambient temperature in absolute darkness