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We speculate that the significant widespread use of AQ in Kenya as an alternative to S/P prior to the use of ACTs may have resulted in the observed apparent maintenance of CQ resistance due to structural similarities between the two drugs [39], but with the advent and acceptability of ACT use within the Kenyan health care community this drug pressure dissipated in the last 5 years

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125 Notably, ELISA demonstrate that IDH1 level is also significantly elevated in the plasma of NSCLC patients, suggesting that it can be used as a potential plasma biomarker

However, other strains of E

doi: 10.1093/hmg/ddaa169 57 NewberryFHsiehSYWilemanTCardingSR