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To assess the half maximal inhibitory concentration (IC50) of FOXO4-DRI on the serum limitation-induced senescent fibroblast and the non-senescent control fibroblast, the fibroblast viability in the 2% FBS induced senescent fibroblast and 10% FBS cultured non-senescent control fibroblast with increasing concentrations of FOXO4-DRI was detected, and the cell viability curves were showed in Supplementary Fig

The micro-channels created by the needles allow the peptide to penetrate deeper layers of the skin, significantly boosting collagen remodeling and speeding up recovery time

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Participation in a registered clinical trial remains the only legitimate route to access these treatments in the UK at present

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