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Ionescu-Tucker and Cotman, 2021)

Studies show IGF-1 supports cognitive function, combats neurodegenerative processes, and enhances synaptic formation and autophagy

Prevalence, fitness, mutation rate, and effect of parental transmission on severity

The ROS Detection Assay Kit was purchased from GENMED Scientifics Inc., USA

Bmal1 KO adipocytes display a distinct pattern via downregulation of circadian rhythm, insulin signalling, glycerolipid metabolism and glutathione metabolism, with upregulation of thermogenesis, autophagy and cAMP signalling (Extended Data Fig