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This method involves forming a primary water-in-oil emulsion, followed by a secondary oil-in-water emulsion

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This makes it a commonly chosen reference compound in studies specifically designed to isolate GH-axis effects

doi: 10.3389/fmicb.2017.02206 94 ZhangJ.YangY.LeiX.WangY.LiY.YangZ.et al

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Alternative options include propylthiouracil, although cross-reactivity with methimazole has been reported, as well as definitive interventions such as radioactive iodine ablation or thyroidectomy