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Johri AM, Htu MF, Heyland DK, Herr JE, Korol J, Froese S, Norman PA, Day AG, Matangi MF, Michos ED, LaHaye SA, Saunders FW, Spence JD

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Impaired insulin signaling Insulin signaling plays a crucial role in maintaining peripheral nerve health, and its impairment significantly contributes to the pathogenesis of DPN

These exploratory aims are not powered to generate meaningful conclusions and can at best be used to show associations, although, ironically, these imaging techniques carry the most potential for deriving biologic insight into modes of therapy failure or resistance