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The Journal of Urology

3.2 Chemical instability under physiological and processing conditions Curcumin is notably unstable in both physiological fluids and during standard processing conditions, undergoing rapid degradation that compromises its therapeutic efficacy and shelf stability

HGH is also known to affect cholesterol levels and, therefore, worsen existing heart conditions

El-Maadawy WH, Hassan M, Hafiz E, Badawy MH, Eldahshan S, AbuSeada AR, El-Shazly MAM, Ghareeb MA (2022) Co-treatment with esculin and erythropoietin protects against renal ischemiareperfusion injury via P2X7 receptor inhibition and PI3K/Akt activation